International researchers have recently published in the journal Nature Genetics, the results of a study that could lead to a significant improvement in the treatment of Type 2 Diabetes.
Researchers have identified a gene called Insulin Receptor Substrate 1 (SRI1). Contrary to recently discovered genes that decrease insulin production from the pancreas, SRI1 decreases the effects of insulin in muscle, liver and fat. It thus influences how the body responds to insulin in the bloodstream.
Type 2 Diabetes mainly affects adults over the age of 40. In 60% of the cases, patients are also overweight, but there are important genetic factors that may also increase the risk of developing the disease.
Type 2 Diabetes is caused by the body’s resistance to insulin, a hormone produced by the pancreas which allows glucose to be absorbed by cells which is then transformed into energy.