The actor, who is best known for his role as vampire Mick St. John in the Moonlight series, will likely star opposite Jennifer Lopez in the upcoming film.
The Back-Up Plan follows a single woman who is desperate to have children. The same day that she undergoes artificial insemination, she meets the man of her dreams.
Filming is set to begin on May 11 in Los Angeles.
We can next see Alex O’Loughlin starring opposite Kate Beckinsale in the thriller Whiteout, opening on September 11.