Leaves of Grass will be the star’s second time to direct, following Keeping the Faith in 2000.
The 38 year-old actor will play twins. One is a professor of philosophy, while the other is a criminal who leads his brother in a story of murder and drugs.
Norton will also be working with his co-star from The Incredible Hulk, Tim Blake Nelson, who will produce the film, which begins shooting on March 8 in New Orleans.
For now, we can next see Edward Norton as Bruce Banner and Hulk in the film which opens on June 13, 2008.