In the film, Smith plays Robert Neville, a brilliant scientist who desperately tries to contain and battle a deadly virus that seems to be unstoppable. Neville believes that he is the last man alive in New York.
The suspense also stars Alice Braga, Salli Richardson-Whitfield, Charlie Tahan and Willow Smith, the daughter of Will Smith.
To watch the trailer for I Am Legend, which was directed by Francis Lawrence (Constantine) and will open in theatres on December 14, click here.