Sarah Michelle Gellar, Chris Evans, Kevin Smith, Patrick Stewart and Zhang Ziyi will all be part of the project.
Zhang Ziyi will provide the voice of the villain Karai, who is the leader of the Foot Ninjas. Sarah Michelle Gellar will play April, who will be a maternal figure for the turtles.
Chris Evans (Fantastic Four) will provide the voice for Casey Jones, a friend of the turtles, and Kevin Smith will play a chef. Patrick Stewart will be the voice of Max Winters, a tech industrialist who has put together an army of monsters.
The voices for the turtles will not be well-known actors. Teenage Mutant Ninja Turtles is expected to open in theatres on March 23.