The star completely contradicted an article that appeared in the magazine Us Weekly (April 18) that stated that the stars are a couple.
The article was titled, "It`s True!" The story went on to say that employees at a California hotel witnessed public acts of affection between the stars.
In an interview Thursday for television`s Access Hollywood, the 41 year-old actor said, "This particular story is completely untrue."
"Because these tabloids are making so much money, and yes, I consider Us Weekly a tabloid, they go to great lengths to corroborate their stories, whether they are true or not." he added.
The story first became news when Britain`s The Sun reported that the two actors would be sharing a room at the Parker Meridian hotel in Palm Springs, California to promote their film Mr. and Mrs. Smith.
In a statement, the magazine said: "Pitt has long denied stories involving his personal life, beginning with reports of trouble in his marriage to Jennifer Aniston prior to the separation. Multiple sources both on and off the record confirmed Pitt and Jolie were physically affectionate in public areas of the resort where they were staying."