The two stars, who also star in the film Ocean’s 13, have joined the cast of the new comedy from the Coen brothers.
According to the Hollywood Reporter, Burn After Reading is the story of a CIA agent who loses a disc that includes a book that he is writing.
Joel and Ethan Coen wrote the screenplay, and filming is set to begin in August.
Ocean’s 13, which stars both Pitt and Clooney, will be presented at the upcoming 60th annual Cannes Film Festival in May.