The 32 year-old star also joins British actress Liz Hurley, who is currently a spokesperson for the Re-Nutriv line.
Paltrow will soon be seen in a multinational ad campaign to celebrate the 10th anniversary of the perfume Pleasure.
A representative for Estée Lauder commented on their newest star, "Gwyneth has been on our radar screen for many years. She’s talented. She’s serious. She’s beautiful. She’s a mother, and she’s respected in her craft."