Later this week, the three men will begin filming the project, according to Variety.
Crossing Over follows the controversial topic of immigrants and those who will do anything to enter into the United States.
Wayne Kramer (The Cooler) has written and will direct the feature film, which will be shot in Los Angeles.
Penn will be making only a cameo in the film, and will be on the set for three days. Ford will play a border agent, and Liotta will play a bureaucrat dealing with the issue of the illegal immigrants.