Marc Jacobs, Giles Deacon, Matthew Williamson and Karl Lagerfeld are working together to come to the aid of the Royal Brompton Hospital in London.
The designers are part of the Heart and Design organisation, which raises funds to purchase equipment for the hospital.
Each designer will create a unique piece, which will be introduced to the public on September 13 during London’s Fashion Week. The designs will then go on auction at Christie’s on September 15.
The proceeds will be used to modernize the hospital, which specialises in heart and lung diseases.