Maguire, 31, just completed working on the film Spider-Man 3. The news comes just months after the film franchise’s female star, Kirsten Dunst, announced that she will no longer star in Spider-Man films.
Maguire explained, "To me it seems like this is a natural point for the team to break up because we have a lot of story conclusions that were going along for the main characters for the first two movies. Maguire added, "It feels like a trilogy to me and it feels like the end."
Despite the announcements from the film’s stars, Sam Raimi, who directed the films, believes that a fourth installment may be possible. Raimi said, "I love Spider-Man. At this moment I’m fascinated with him."
Spider-Man 3 will open in theatres in May.