The celebrity talk show host went to Los Angeles, on the set of Desperate Housewives to record an episode with Teri Hatcher and her co-stars.
After one day on the set with all the beauties of this series, Oprah exclaimed, "I can’t believe you have a street with that many housewives and nobody has a butt. Who has a street with that many thin women?"
In this episode Oprah plays a woman who arrives in the neighbourhood, and eventually takes off after finding out the secrets of all the women in the neighbourhood.
After this experience she stated, "I thought I was done with my acting days, but I loved being a part of the Desperate Housewives so much that I’m thinking I might do something else soon."