The rocker’s separation comes after 17 years with common-law wife, Teresa.
The 56 year old singer, father of actress Liv Tyler from a previous relationship, has asked for his family to be left alone during this difficult time.
He said: "My wife and I are currently separated. We’re just a family trying to work through a difficult time. A little privacy and sensitivity – for Teresa, my children and myself – would be nice."
The couple have 2 children together, Chelsea, 16, and Taj, 13.