According to the Hollywood Reporter, the duo will be working together to produce a series for cable channel HBO.
The two, who are extremely active in humanitarian causes, have decided to produce the series, which will follow the story of an international humanitarian aid service, which follows individuals as they enter dangerous areas in order to help others.
The project is being written by Scott Burns, who co-wrote The Bourne Ultimatum and produced the documentary An Inconvenient Truth with Al Gore.
After some time in New York, where Pitt was filming Burn After Reading, the Pitt-Jolie family returned to Los Angeles where Jolie is working under the direction of Clint Eastwood in the historical drama The Changeling.